Validation of the animal model of bipolar disorder induced by Ouabain: face, construct and predictive perspectives

A particular challenge in the development of a bipolar disorder (BD) model in animals is the complicated clinical course of the condition, characterized by manic, depressive and mixed mood episodes. Ouabain (OUA) is an inhibitor of Na(+)/K(+)-ATPase enzyme. Intracerebroventricular (ICV) injection of...

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Detalles Bibliográficos
Autores principales: Valvassori, Samira S., Dal-Pont, Gustavo C., Resende, Wilson R., Varela, Roger B., Lopes-Borges, Jéssica, Cararo, José Henrique, Quevedo, João
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548776/
https://www.ncbi.nlm.nih.gov/pubmed/31164628
http://dx.doi.org/10.1038/s41398-019-0494-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548776/
https://www.ncbi.nlm.nih.gov/pubmed/31164628
http://dx.doi.org/10.1038/s41398-019-0494-6

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