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Validation of the animal model of bipolar disorder induced by Ouabain: face, construct and predictive perspectives
A particular challenge in the development of a bipolar disorder (BD) model in animals is the complicated clinical course of the condition, characterized by manic, depressive and mixed mood episodes. Ouabain (OUA) is an inhibitor of Na(+)/K(+)-ATPase enzyme. Intracerebroventricular (ICV) injection of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548776/ https://www.ncbi.nlm.nih.gov/pubmed/31164628 http://dx.doi.org/10.1038/s41398-019-0494-6 |