Both aldosterone and spironolactone can modulate the intracellular ACE/ANG II/AT1 and ACE2/ANG (1‐7)/MAS receptor axes in human mesangial cells

The kidney is an important target of the renin‐ANG‐aldosterone system (RAAS). To date, several studies have demonstrated the existence of a local RAAS in various tissues, including the renal tissue. The mineralocorticoid aldosterone is known to play a critical role in the classical RAAS; however, it...

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Detalles Bibliográficos
Autores principales: Stoll, Danielle, Yokota, Rodrigo, Sanches Aragão, Danielle, Casarini, Dulce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548847/
https://www.ncbi.nlm.nih.gov/pubmed/31165585
http://dx.doi.org/10.14814/phy2.14105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548847/
https://www.ncbi.nlm.nih.gov/pubmed/31165585
http://dx.doi.org/10.14814/phy2.14105

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