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Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection

Meningococcal meningitis is a severe central nervous system infection that occurs when Neisseria meningitidis (Nm) penetrates brain endothelial cells (BECs) of the meningeal blood-cerebrospinal fluid barrier. As a human-specific pathogen, in vivo models are greatly limited and pose a significant cha...

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Detalles Bibliográficos
Autores principales: Martins Gomes, Sara F., Westermann, Alexander J., Sauerwein, Till, Hertlein, Tobias, Förstner, Konrad U., Ohlsen, Knut, Metzger, Marco, Shusta, Eric V., Kim, Brandon J., Appelt-Menzel, Antje, Schubert-Unkmeir, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548865/
https://www.ncbi.nlm.nih.gov/pubmed/31191497
http://dx.doi.org/10.3389/fmicb.2019.01181