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Risk Factors for Indeterminate Interferon-Gamma Release Assay for the Diagnosis of Tuberculosis in Children—A Systematic Review and Meta-Analysis

Background: Interferon-gamma release assays (IGRA) are well-established immunodiagnostic tests for tuberculosis (TB) in adults. In children these tests are associated with higher rates of false-negative and indeterminate results. Age is presumed to be one factor influencing cytokine release and ther...

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Detalles Bibliográficos
Autores principales: Meier, Noëmi R., Volken, Thomas, Geiger, Marc, Heininger, Ulrich, Tebruegge, Marc, Ritz, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548884/
https://www.ncbi.nlm.nih.gov/pubmed/31192175
http://dx.doi.org/10.3389/fped.2019.00208