Cargando…

Effective Delivery of Hypertrophic miRNA Inhibitor by Cholesterol‐Containing Nanocarriers for Preventing Pressure Overload Induced Cardiac Hypertrophy

Persistent cardiac hypertrophy causes heart failure and sudden death. Gene therapy is a promising intervention for this disease, but is limited by the lack of effective delivery systems. Herein, it is reported that CHO‐PGEA (cholesterol (CHO)‐terminated ethanolamine‐aminated poly(glycidyl methacryla...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhi, Ying, Xu, Chen, Sui, Dandan, Du, Jie, Xu, Fu‐Jian, Li, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548964/
https://www.ncbi.nlm.nih.gov/pubmed/31179215
http://dx.doi.org/10.1002/advs.201900023