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Kidney cytosine methylation changes improve renal function decline estimation in patients with diabetic kidney disease

Epigenetic changes might provide the biological explanation for the long-lasting impact of metabolic alterations of diabetic kidney disease development. Here we examined cytosine methylation of human kidney tubules using Illumina Infinium 450 K arrays from 91 subjects with and without diabetes and v...

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Detalles Bibliográficos
Autores principales: Gluck, Caroline, Qiu, Chengxiang, Han, Sang Youb, Palmer, Matthew, Park, Jihwan, Ko, Yi-An, Guan, Yuting, Sheng, Xin, Hanson, Robert L., Huang, Jing, Chen, Yong, Park, Ae Seo Deok, Izquierdo, Maria Concepcion, Mantzaris, Ioannis, Verma, Amit, Pullman, James, Li, Hongzhe, Susztak, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549146/
https://www.ncbi.nlm.nih.gov/pubmed/31165727
http://dx.doi.org/10.1038/s41467-019-10378-8