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RGD-independent binding of Russell’s Viper venom Kunitz-type protease inhibitors to platelet GPIIb/IIIa receptor
This study elucidates the platelet-modulating properties of two snake venom Kunitz-type serine protease inhibitors, Rusvikunin and Rusvikunin-II, from Russell’s Viper venom, their native and reconstituted complexes, and two synthetic custom peptides (developed from the platelet-binding region of Rus...
| Auteurs principaux: | , , |
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| Format: | Online Article Texte |
| Langue: | English |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549151/ https://www.ncbi.nlm.nih.gov/pubmed/31165757 http://dx.doi.org/10.1038/s41598-019-44767-2 |