Disordered RNA chaperones can enhance nucleic acid folding via local charge screening

RNA chaperones are proteins that aid in the folding of nucleic acids, but remarkably, many of these proteins are intrinsically disordered. How can these proteins function without a well-defined three-dimensional structure? Here, we address this question by studying the hepatitis C virus core protein...

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Detalles Bibliográficos
Autores principales: Holmstrom, Erik D., Liu, Zhaowei, Nettels, Daniel, Best, Robert B., Schuler, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549165/
https://www.ncbi.nlm.nih.gov/pubmed/31165735
http://dx.doi.org/10.1038/s41467-019-10356-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549165/
https://www.ncbi.nlm.nih.gov/pubmed/31165735
http://dx.doi.org/10.1038/s41467-019-10356-0

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