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Disordered RNA chaperones can enhance nucleic acid folding via local charge screening
RNA chaperones are proteins that aid in the folding of nucleic acids, but remarkably, many of these proteins are intrinsically disordered. How can these proteins function without a well-defined three-dimensional structure? Here, we address this question by studying the hepatitis C virus core protein...
Autores principales: | Holmstrom, Erik D., Liu, Zhaowei, Nettels, Daniel, Best, Robert B., Schuler, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549165/ https://www.ncbi.nlm.nih.gov/pubmed/31165735 http://dx.doi.org/10.1038/s41467-019-10356-0 |
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