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SAGA DUBm-mediated surveillance regulates prompt export of stress-inducible transcripts for proteostasis

During stress, prompt export of stress-inducible transcripts is critical for cell survival. Here, we characterize a function of the SAGA (Spt-Ada-Gcn5 acetyltransferase) deubiquitylating module (DUBm) in monitoring messenger ribonucleoprotein (mRNP) biogenesis to regulate non-canonical mRNA export o...

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Detalles Bibliográficos
Autores principales: Kim, Minhoo, Choi, Yoonjung, Kim, Harim, Lee, Daeyoup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549176/
https://www.ncbi.nlm.nih.gov/pubmed/31165730
http://dx.doi.org/10.1038/s41467-019-10350-6