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SNAI1 recruits HDAC1 to suppress SNAI2 transcription during epithelial to mesenchymal transition

Aberrant activation of epithelial to mesenchymal transition (EMT) associated factors were highly correlated with increased mortality in cancer patients. SNAIL family of transcriptional repressors comprised of three members, each of which were essentially associated with gastrulation and neural crest...

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Detalles Bibliográficos
Autores principales: Sundararajan, Vignesh, Tan, Ming, Tan, Tuan Zea, Ye, Jieru, Thiery, Jean Paul, Huang, Ruby Yun-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549180/
https://www.ncbi.nlm.nih.gov/pubmed/31165775
http://dx.doi.org/10.1038/s41598-019-44826-8