SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes

The SARS (severe acute respiratory syndrome) outbreak was caused by a coronavirus (CoV) named the SARS-CoV. SARS pathology is propagated both by direct cytotoxic effects of the virus and aberrant activation of the innate immune response. Here, we identify several mechanisms by which a SARS-CoV open...

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Detalles Bibliográficos
Autores principales: Shi, Chong-Shan, Nabar, Neel R., Huang, Ning-Na, Kehrl, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549181/
https://www.ncbi.nlm.nih.gov/pubmed/31231549
http://dx.doi.org/10.1038/s41420-019-0181-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549181/
https://www.ncbi.nlm.nih.gov/pubmed/31231549
http://dx.doi.org/10.1038/s41420-019-0181-7

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