Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition

3-β-hydroxysteroid-Δ(8), Δ(7)-isomerase, known as Emopamil-Binding Protein (EBP), is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis, autophagy, oligodendrocyte formation. The mutation on EBP can cause Conradi-Hunermann syndrome, an inborn error. Interestingly, EBP bin...

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Detalles Bibliográficos
Autores principales: Long, Tao, Hassan, Abdirahman, Thompson, Bonne M, McDonald, Jeffrey G, Wang, Jiawei, Li, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549186/
https://www.ncbi.nlm.nih.gov/pubmed/31165728
http://dx.doi.org/10.1038/s41467-019-10279-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549186/
https://www.ncbi.nlm.nih.gov/pubmed/31165728
http://dx.doi.org/10.1038/s41467-019-10279-w

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