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Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition
3-β-hydroxysteroid-Δ(8), Δ(7)-isomerase, known as Emopamil-Binding Protein (EBP), is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis, autophagy, oligodendrocyte formation. The mutation on EBP can cause Conradi-Hunermann syndrome, an inborn error. Interestingly, EBP bin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549186/ https://www.ncbi.nlm.nih.gov/pubmed/31165728 http://dx.doi.org/10.1038/s41467-019-10279-w |