Loss of transglutaminase 2 sensitizes for diet-induced obesity-related inflammation and insulin resistance due to enhanced macrophage c-Src signaling

Transglutaminase 2 (TG2) is a multifunctional protein that promotes clearance of apoptotic cells (efferocytosis) acting as integrin β(3) coreceptor. Accumulating evidence indicates that defective efferocytosis contributes to the development of chronic inflammatory diseases. Obesity is characterized...

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Detalles Bibliográficos
Autores principales: Sághy, Tibor, Köröskényi, Krisztina, Hegedűs, Krisztina, Antal, Miklós, Bankó, Csaba, Bacsó, Zsolt, Papp, Attila, Stienstra, Rinke, Szondy, Zsuzsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549190/
https://www.ncbi.nlm.nih.gov/pubmed/31165747
http://dx.doi.org/10.1038/s41419-019-1677-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549190/
https://www.ncbi.nlm.nih.gov/pubmed/31165747
http://dx.doi.org/10.1038/s41419-019-1677-z

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