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H7N9 influenza A virus activation of necroptosis in human monocytes links innate and adaptive immune responses

We previously demonstrated that avian influenza A H7N9 virus preferentially infected CD14(+) monocyte in human peripheral blood mononuclear cells (PBMCs), which led to apoptosis. To better understand H7N9 pathogenesis in relation to monocyte cell death, we showed here that extensive phosphorylation...

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Detalles Bibliográficos
Autores principales: Lee, Andrew C. Y., Zhang, Anna J. X., Chu, Hin, Li, Can, Zhu, Houshun, Mak, Winger W. N., Chen, Yanxia, Kok, Kin-Hang, To, Kelvin K. W., Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549191/
https://www.ncbi.nlm.nih.gov/pubmed/31165725
http://dx.doi.org/10.1038/s41419-019-1684-0