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Prostaglandin E1 Alleviates Cognitive Dysfunction in Chronic Cerebral Hypoperfusion Rats by Improving Hemodynamics

Compensatory vascular mechanisms can restore cerebral blood flow (CBF) but fail to protect against chronic cerebral hypoperfusion (CCH)-mediated neuronal damage and cognitive impairment. Prostaglandin E1 (PGE1) is known as a vasodilator to protect against ischemic injury in animal models, but its pr...

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Detalles Bibliográficos
Autores principales: Xie, Xiaomei, Lu, Weibiao, Chen, Yuanfang, Tsang, Chi Kwan, Liang, Jianye, Li, Wenxian, Jing, Zhen, Liao, Yu, Huang, Li’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549528/
https://www.ncbi.nlm.nih.gov/pubmed/31191236
http://dx.doi.org/10.3389/fnins.2019.00549