Cargando…
Prostaglandin E1 Alleviates Cognitive Dysfunction in Chronic Cerebral Hypoperfusion Rats by Improving Hemodynamics
Compensatory vascular mechanisms can restore cerebral blood flow (CBF) but fail to protect against chronic cerebral hypoperfusion (CCH)-mediated neuronal damage and cognitive impairment. Prostaglandin E1 (PGE1) is known as a vasodilator to protect against ischemic injury in animal models, but its pr...
Autores principales: | Xie, Xiaomei, Lu, Weibiao, Chen, Yuanfang, Tsang, Chi Kwan, Liang, Jianye, Li, Wenxian, Jing, Zhen, Liao, Yu, Huang, Li’an |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549528/ https://www.ncbi.nlm.nih.gov/pubmed/31191236 http://dx.doi.org/10.3389/fnins.2019.00549 |
Ejemplares similares
-
Dl-3-n-Butylphthalide Treatment Enhances Hemodynamics and Ameliorates Memory Deficits in Rats with Chronic Cerebral Hypoperfusion
por: Xiong, Zhilin, et al.
Publicado: (2017) -
Chronic cerebral hypoperfusion induces vascular plasticity and hemodynamics but also neuronal degeneration and cognitive impairment
por: Jing, Zhen, et al.
Publicado: (2015) -
Comprehensive Evaluation of White Matter Damage and Neuron Death and Whole-Transcriptome Analysis of Rats With Chronic Cerebral Hypoperfusion
por: Li, Wenxian, et al.
Publicado: (2019) -
Corrigendum: Comprehensive Evaluation of White Matter Damage and Neuron Death and Whole-Transcriptome Analysis of Rats With Chronic Cerebral Hypoperfusion
por: Li, Wenxian, et al.
Publicado: (2020) -
Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis
por: Li, Wenxian, et al.
Publicado: (2019)