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Gene Expression and DNA Methylation Alterations During Non-alcoholic Steatohepatitis-Associated Liver Carcinogenesis

Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers. HCC is characterized by an acquisition of multiple abnormal phenotypes driven by genetic and epigenetic alterations, especially abnormal DNA methylation. Most of the existing clinical and experimental reports provide only a...

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Detalles Bibliográficos
Autores principales: Dreval, Kostiantyn, Tryndyak, Volodymyr, de Conti, Aline, Beland, Frederick A., Pogribny, Igor P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549534/
https://www.ncbi.nlm.nih.gov/pubmed/31191608
http://dx.doi.org/10.3389/fgene.2019.00486