Detection of a cryptic NUP214/ABL1 gene fusion by mate-pair sequencing (MPseq) in a newly diagnosed case of pediatric T-lymphoblastic leukemia

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematopoietic neoplasm involving the bone marrow and blood that accounts for ∼15% of childhood and 25% of adult ALL. Whereas multiple, recurrent genetic abnormalities have been described in T-ALL, their clinical significance is unclear or...

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Detalles Bibliográficos
Autores principales: Peterson, Jess F., Pitel, Beth A., Smoley, Stephanie A., Smadbeck, James B., Johnson, Sarah H., Vasmatzis, George, Koon, Sarah J., Webley, Matthew R., McGrath, Mary, Bayerl, Michael G., Baughn, Linda B., Rowsey, Ross A., Ketterling, Rhett P., Greipp, Patricia T., Hoppman, Nicole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Precision Medicine in Practice
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549564/
https://www.ncbi.nlm.nih.gov/pubmed/30936193
http://dx.doi.org/10.1101/mcs.a003533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549564/
https://www.ncbi.nlm.nih.gov/pubmed/30936193
http://dx.doi.org/10.1101/mcs.a003533

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