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Circulating tumor DNA dynamics using patient-customized assays are associated with outcome in neoadjuvantly treated breast cancer

Pathological complete response (pCR) is an accurate predictor of good outcome following neoadjuvant chemotherapy (NAC) for locally advanced breast cancer. The presence of circulating-tumor DNA (ctDNA) has recently been reported to be strongly predictive of poor outcome in similar patient groups. We...

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Detalles Bibliográficos
Autores principales: Butler, Timothy M., Boniface, Christopher T., Johnson-Camacho, Katie, Tabatabaei, Shaadi, Melendez, Daira, Kelley, Taylor, Gray, Joe, Corless, Christopher L., Spellman, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549569/
https://www.ncbi.nlm.nih.gov/pubmed/30833418
http://dx.doi.org/10.1101/mcs.a003772