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Discovery of Furanoquinone Derivatives as a Novel Class of DNA Polymerase and Gyrase Inhibitors for MRSA Eradication in Cutaneous Infection

Methicillin-resistant Staphylococcus aureus (MRSA) is the primary microbe responsible for skin infections that are particularly difficult to eradicate. This study sought to inhibit planktonic and biofilm MRSA using furanoquinone-derived compounds containing imine moiety. A total of 19 furanoquinone...

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Detalles Bibliográficos
Autores principales: Yang, Shih-Chun, Tang, Kai-Wei, Lin, Chih-Hung, Alalaiwe, Ahmed, Tseng, Chih-Hua, Fang, Jia-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549599/
https://www.ncbi.nlm.nih.gov/pubmed/31191504
http://dx.doi.org/10.3389/fmicb.2019.01197