Impact of EGFR genotype on the efficacy of osimertinib in EGFR tyrosine kinase inhibitor-resistant patients with non-small cell lung cancer: a prospective observational study

Purpose: A T790M of the epidermal growth factor receptor (EGFR) is the most frequently encountered mutation conferring acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC). The aim of this study was to assess the differential clinical outcomes of osimer...

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Detalles Bibliográficos
Autores principales: Igawa, Satoshi, Ono, Taihei, Kasajima, Masashi, Ishihara, Mikiko, Hiyoshi, Yasuhiro, Kusuhara, Seiichiro, Nishinarita, Noriko, Fukui, Tomoya, Kubota, Masaru, Sasaki, Jiichiro, Hisashi, Mitsufuji, Yokoba, Masanori, Katagiri, Masato, Naoki, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549661/
https://www.ncbi.nlm.nih.gov/pubmed/31213907
http://dx.doi.org/10.2147/CMAR.S207170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549661/
https://www.ncbi.nlm.nih.gov/pubmed/31213907
http://dx.doi.org/10.2147/CMAR.S207170

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