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Loss of ARID1A promotes proliferation, migration and invasion via the Akt signaling pathway in NPC

Background: AT-rich interactive domain-containing protein 1A (ARID1A) is a member of the switch/sucrose nonfermentable chromatin remodeling complex, which has been observed to be mutated in various tumors. The loss of ARID1A is reported to be frequently associated with PI3K/Akt pathway activation. O...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Wang, Xiaoyu, Yang, Junjun, Duan, Jingling, Wu, Zhen, Yang, Fan, Zhang, Xiaoling, Xiao, Shengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549766/
https://www.ncbi.nlm.nih.gov/pubmed/31213911
http://dx.doi.org/10.2147/CMAR.S207329