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Induction of pro-inflammatory cytokines by 29-kDa FN-f via cGAS/STING pathway

The cGAS-STING pathway plays an important role in pathogen-induced activation of the innate immune response. The 29-kDa amino-terminal fibronectin fragment (29-kDa FN-f) found predominantly in the synovial fluid of osteoarthritis (OA) patients increases the expression of catabolic factors via the to...

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Detalles Bibliográficos
Autores principales: Hwang, Hyun Sook, Lee, Mi Hyun, Choi, Min Ha, Kim, Hyun Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549918/
https://www.ncbi.nlm.nih.gov/pubmed/31068249
http://dx.doi.org/10.5483/BMBRep.2019.52.5.072