Epigenetic silencing of SOCS5 potentiates JAK‐STAT signaling and progression of T‐cell acute lymphoblastic leukemia

Activating mutations in cytokine receptors and transcriptional regulators govern aberrant signal transduction in T‐cell lineage acute lymphoblastic leukemia (T‐ALL). However, the roles played by suppressors of cytokine signaling remain incompletely understood. We examined the regulatory roles of sup...

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Detalles Bibliográficos
Autores principales: Sharma, Nitesh D., Nickl, Christian K., Kang, Huining, Ornatowski, Wojciech, Brown, Roger, Ness, Scott A., Loh, Mignon L., Mullighan, Charles G., Winter, Stuart S., Hunger, Stephen P., Cannon, Judy L., Matlawska‐Wasowska, Ksenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549933/
https://www.ncbi.nlm.nih.gov/pubmed/30974024
http://dx.doi.org/10.1111/cas.14021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549933/
https://www.ncbi.nlm.nih.gov/pubmed/30974024
http://dx.doi.org/10.1111/cas.14021

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