Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish

DYRK1A is a major causative gene in Down syndrome (DS). Reduced incidence of solid tumors such as neuroblastoma in DS patients and increased vascular anomalies in DS fetuses suggest a potential role of DYRK1A in angiogenic processes, but in vivo evidence is still scarce. Here, we used zebrafish dyrk...

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Detalles Bibliográficos
Autores principales: Cho, Hyun-Ju, Lee, Jae-Geun, Kim, Jong-Hwan, Kim, Seon-Young, Huh, Yang Hoon, Kim, Hyo-Jeong, Lee, Kyu-Sun, Yu, Kweon, Lee, Jeong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550036/
https://www.ncbi.nlm.nih.gov/pubmed/31043432
http://dx.doi.org/10.1242/dmm.037044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550036/
https://www.ncbi.nlm.nih.gov/pubmed/31043432
http://dx.doi.org/10.1242/dmm.037044

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