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Re-evaluation of the causes of variation among mouse aggregation chimaeras

The composition of adult mouse aggregation chimaeras is much more variable than X-inactivation mosaics. An early theoretical model proposed that almost all the extra variation in chimaeras arises, before X-inactivation occurs, by spatially constrained, geometrical allocation of inner cell mass (ICM)...

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Detalles Bibliográficos
Autores principales: West, John D., Tang, Pin-Chi, Everett, Clare A., MacKay, Gillian E., Flockhart, Jean H., Keighren, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550066/
https://www.ncbi.nlm.nih.gov/pubmed/31147312
http://dx.doi.org/10.1242/bio.042804