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Intercellular transfer of P-glycoprotein mediates the formation of stable multi-drug resistance in human bladder cancer BIU-87 cells

We investigated the biological characteristics of acquired drug-resistant cells (AqMDRs) formed by intercellular P-glycoprotein (P-gp) transfer and whether AqMDRs can form stable drug-resistant strains. Drug-sensitive BIU-87 cells were co-cultured with doxorubicin (DOX)-resistant derivative BIU-87/D...

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Detalles Bibliográficos
Autores principales: Cheng, Xiao-Zhi, Zhou, Hui-Liang, Tang, Song-Xi, Jiang, Tao, Chen, Qin, Gao, Rui, Ding, Yi-Lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550073/
https://www.ncbi.nlm.nih.gov/pubmed/30967374
http://dx.doi.org/10.1242/bio.041889