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Intercellular transfer of P-glycoprotein mediates the formation of stable multi-drug resistance in human bladder cancer BIU-87 cells
We investigated the biological characteristics of acquired drug-resistant cells (AqMDRs) formed by intercellular P-glycoprotein (P-gp) transfer and whether AqMDRs can form stable drug-resistant strains. Drug-sensitive BIU-87 cells were co-cultured with doxorubicin (DOX)-resistant derivative BIU-87/D...
Autores principales: | Cheng, Xiao-Zhi, Zhou, Hui-Liang, Tang, Song-Xi, Jiang, Tao, Chen, Qin, Gao, Rui, Ding, Yi-Lang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550073/ https://www.ncbi.nlm.nih.gov/pubmed/30967374 http://dx.doi.org/10.1242/bio.041889 |
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