Cargando…

Longitudinal characterization of diet-induced genetic murine models of non-alcoholic steatohepatitis with metabolic, histological, and transcriptomic hallmarks of human patients

Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disease in the Western world. Currently, only a few animal models show both the metabolic and histological features of human NASH. We aimed to explore murine NASH models in a time dependent manner that exhibit metabolic, histological and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Abe, Naomichi, Kato, Sayuka, Tsuchida, Takuma, Sugimoto, Kanami, Saito, Ryuta, Verschuren, Lars, Kleemann, Robert, Oka, Kozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550083/
https://www.ncbi.nlm.nih.gov/pubmed/31023717
http://dx.doi.org/10.1242/bio.041251