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Longitudinal characterization of diet-induced genetic murine models of non-alcoholic steatohepatitis with metabolic, histological, and transcriptomic hallmarks of human patients
Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disease in the Western world. Currently, only a few animal models show both the metabolic and histological features of human NASH. We aimed to explore murine NASH models in a time dependent manner that exhibit metabolic, histological and t...
Autores principales: | Abe, Naomichi, Kato, Sayuka, Tsuchida, Takuma, Sugimoto, Kanami, Saito, Ryuta, Verschuren, Lars, Kleemann, Robert, Oka, Kozo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550083/ https://www.ncbi.nlm.nih.gov/pubmed/31023717 http://dx.doi.org/10.1242/bio.041251 |
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