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PGC1α/CEBPB/CPT1A axis promotes radiation resistance of nasopharyngeal carcinoma through activating fatty acid oxidation

The PPAR coactivator‐1α (PGC1α) is an important transcriptional co‐activator in control of fatty acid metabolism. Mitochondrial fatty acid oxidation (FAO) is the primary pathway for the degradation of fatty acids and promotes NADPH and ATP production. Our previous study demonstrated that upregulatio...

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Detalles Bibliográficos
Autores principales: Du, Qianqian, Tan, Zheqiong, Shi, Feng, Tang, Min, Xie, Longlong, Zhao, Lin, Li, Yueshuo, Hu, Jianmin, Zhou, Min, Bode, Ann, Luo, Xiangjian, Cao, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550130/
https://www.ncbi.nlm.nih.gov/pubmed/30945396
http://dx.doi.org/10.1111/cas.14011