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High-Throughput Recovery and Characterization of Metagenome-Derived Glycoside Hydrolase-Containing Clones as a Resource for Biocatalyst Development

Functional metagenomics is a powerful tool for both the discovery and development of biocatalysts. This study presents the high-throughput functional screening of 22 large-insert fosmid libraries containing over 300,000 clones sourced from natural and engineered ecosystems, characterization of activ...

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Detalles Bibliográficos
Autores principales: Armstrong, Zachary, Liu, Feng, Kheirandish, Sam, Chen, Hong-Ming, Mewis, Keith, Duo, Tianmeng, Morgan-Lang, Connor, Hallam, Steven J., Withers, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550366/
https://www.ncbi.nlm.nih.gov/pubmed/31164449
http://dx.doi.org/10.1128/mSystems.00082-19