TGF-β induces liver fibrosis via miRNA-181a-mediated down regulation of augmenter of liver regeneration in hepatic stellate cells

OBJECTIVE: To study the role of miRNA-181a and augmenter of liver regeneration in TGF-β-induced fibrosis in hepatic stellate cells. METHODS: LX2 cells were treated with 20 ng/ml TGF-β for 24 h. miRNA-181a, ALR plasmid and empty vectors were transfected using siPORT NeoFx reagent. Cells were harveste...

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Detalles Bibliográficos
Autores principales: Gupta, Parul, Sata, Teja Naveen, Yadav, Ajay K., Mishra, Amit, Vats, Nisha, Hossain, Md. Musa, Sanal, M. G., Venugopal, Senthil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550375/
https://www.ncbi.nlm.nih.gov/pubmed/31166951
http://dx.doi.org/10.1371/journal.pone.0214534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550375/
https://www.ncbi.nlm.nih.gov/pubmed/31166951
http://dx.doi.org/10.1371/journal.pone.0214534

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