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Enhanced histamine-induced itch in diacylglycerol kinase iota knockout mice

Subsets of small-diameter dorsal root ganglia (DRG) neurons detect pruritogenic (itch-causing) and algogenic (pain-causing) stimuli and can be activated or sensitized by chemical mediators. Many of these chemical mediators activate receptors that are coupled to lipid hydrolysis and diacylglycerol (D...

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Detalles Bibliográficos
Autores principales: Bartsch, Victoria Brings, Niehaus, Jesse K., Taylor-Blake, Bonnie, Zylka, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550402/
https://www.ncbi.nlm.nih.gov/pubmed/31167004
http://dx.doi.org/10.1371/journal.pone.0217819