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Whole-genome sequencing based on formalin-fixed paraffin-embedded endomyocardial biopsies for genetic studies on outcomes after heart transplantation

BACKGROUND: Whole-genome sequencing (WGS) of heart transplant recipient- and donor-derived cardiac biopsies may facilitate organ matching, graft failure prediction, and immunotolerance research. The objective of this study was to determine the feasibility of WGS based on formalin-fixed paraffin-embe...

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Detalles Bibliográficos
Autores principales: Zar, Gustav, Smith, J. Gustav, Smith, Maya Landenhed, Andersson, Bodil, Nilsson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550412/
https://www.ncbi.nlm.nih.gov/pubmed/31166960
http://dx.doi.org/10.1371/journal.pone.0217747