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Efficient algorithms to discover alterations with complementary functional association in cancer

Recent large cancer studies have measured somatic alterations in an unprecedented number of tumours. These large datasets allow the identification of cancer-related sets of genetic alterations by identifying relevant combinatorial patterns. Among such patterns, mutual exclusivity has been employed b...

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Detalles Bibliográficos
Autores principales: Sarto Basso, Rebecca, Hochbaum, Dorit S., Vandin, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550413/
https://www.ncbi.nlm.nih.gov/pubmed/31120875
http://dx.doi.org/10.1371/journal.pcbi.1006802