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Efficient algorithms to discover alterations with complementary functional association in cancer
Recent large cancer studies have measured somatic alterations in an unprecedented number of tumours. These large datasets allow the identification of cancer-related sets of genetic alterations by identifying relevant combinatorial patterns. Among such patterns, mutual exclusivity has been employed b...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550413/ https://www.ncbi.nlm.nih.gov/pubmed/31120875 http://dx.doi.org/10.1371/journal.pcbi.1006802 |