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Clonorchis sinensis excretory-secretory products increase malignant characteristics of cholangiocarcinoma cells in three-dimensional co-culture with biliary ductal plates

Clonorchis sinensis is a carcinogenic human liver fluke, prolonged infection which provokes chronic inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma (CCA). These effects are driven by direct physical damage caused by the worms, as well as chemical irritation fro...

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Detalles Bibliográficos
Autores principales: Won, Jihee, Cho, Youngkyu, Lee, Dahyun, Jeon, Bo Young, Ju, Jung-Won, Chung, Seok, Pak, Jhang Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550432/
https://www.ncbi.nlm.nih.gov/pubmed/31121000
http://dx.doi.org/10.1371/journal.ppat.1007818