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Stress-Induced Changes in the Lipid Microenvironment of β-(1,3)-d-Glucan Synthase Cause Clinically Important Echinocandin Resistance in Aspergillus fumigatus

Aspergillus fumigatus is a leading cause of invasive fungal infections. Resistance to first-line triazole antifungals has led to therapy with echinocandin drugs. Recently, we identified several high-minimum-effective-concentration (MEC) A. fumigatus clinical isolates from patients failing echinocand...

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Detalles Bibliográficos
Autores principales:	Satish, Shruthi, Jiménez-Ortigosa, Cristina, Zhao, Yanan, Lee, Min Hee, Dolgov, Enriko, Krüger, Thomas, Park, Steven, Denning, David W., Kniemeyer, Olaf, Brakhage, Axel A., Perlin, David S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550521/ https://www.ncbi.nlm.nih.gov/pubmed/31164462 http://dx.doi.org/10.1128/mBio.00779-19

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