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Evolution of Superinfection Immunity in Cluster A Mycobacteriophages

Temperate phages encode an immunity system to control lytic gene expression during lysogeny. This gene regulatory circuit consists of multiple interacting genetic elements, and although it is essential for controlling phage growth, it is subject to conflicting evolutionary pressures. During superinf...

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Detalles Bibliográficos
Autores principales: Mavrich, Travis N., Hatfull, Graham F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550527/
https://www.ncbi.nlm.nih.gov/pubmed/31164468
http://dx.doi.org/10.1128/mBio.00971-19