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Decreased expression of circ_0020397 in intracranial aneurysms may be contributing to decreased vascular smooth muscle cell proliferation via increased expression of miR-138 and subsequent decreased KDR expression

Dysfunction of vascular smooth muscle cells (VSMCs) mediates intracranial aneurysm (IA). KDR is reported to alleviate IA progression via promoting VSMC proliferation, while the upstream regulators are still unclear. Arterial wall tissues at the aneurysm site from 12 patients were obtained. The real-...

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Detalles Bibliográficos
Autores principales: Wang, Yushe, Wang, Yong, Li, Yu, Wang, Bin, Miao, Zhuang, Liu, Xianzhi, Ma, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550538/
https://www.ncbi.nlm.nih.gov/pubmed/31096819
http://dx.doi.org/10.1080/19336918.2019.1619432