N3ICD with the transmembrane domain can effectively inhibit EMT by correcting the position of tight/adherens junctions

EMT allows a polarized epithelium to lose epithelial integrity and acquire mesenchymal characteristics. Previously, we found that overexpression of the intracellular domain of Notch3 (N3ICD) can inhibit EMT in breast cancer cells. In this study, we aimed to elucidate the influence of N3ICD or N3ICD...

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Detalles Bibliográficos
Autores principales: Tan, Junyu, Zhang, Xixun, Xiao, Wenjun, Liu, Xiong, Li, Chun, Guo, Yuxian, Xiong, Wei, Li, Yaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550553/
https://www.ncbi.nlm.nih.gov/pubmed/31096822
http://dx.doi.org/10.1080/19336918.2019.1619958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550553/
https://www.ncbi.nlm.nih.gov/pubmed/31096822
http://dx.doi.org/10.1080/19336918.2019.1619958

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