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MON-349 HIV and Asthma: What Could Go Wrong? A Case of Adrenal Insufficiency

Introduction: CYP3A4 is the principal enzyme of cytochrome P450 and is the primary metabolic step for the degradation of corticosteroids. Cobicistat is a potent CYP3A4 inhibitor, it is used to increase the levels of antiretrovirals in the treatment of HIV. It is currently available as part of a fixe...

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Detalles Bibliográficos
Autores principales: Zuniga, Gabriela, Rios, Paola, Manzano, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550674/
http://dx.doi.org/10.1210/js.2019-MON-349