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MON-465 SST2 Trafficking Through The Cytoskeleton: Role Of Scaffolding Proteins Filamin A And β-arrestin 2

The high expression level of somatostatin receptor 2 (SST2) in growth hormone (GH)-secreting tumors represents the rationale for the clinical use of somatostatin analogs (SSAs) in acromegaly. However, about one third of patients displays resistance to SSAs and, to date, the underlying molecular mech...

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Detalles Bibliográficos
Autores principales: Treppiedi, Donatella, Giardino, Elena, Catalano, Rosa, Mangili, Federica, Spada, Anna, Arosio, Maura, Mantovani, Giovanna, Peverelli, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550813/
http://dx.doi.org/10.1210/js.2019-MON-465