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MON-487 Simultaneous Monitoring of 13 IGF-1 Variants in a Clinical Mass Spectrometry Assay

In the clinical laboratory, identification and quantification of intact proteins by high resolution accurate mass (HRAM) mass spectrometry (MS) is a highly specific and robust technique. However, protein variants with mass-to-charge ratios (m/z) differing from the wild type are not measured. In addi...

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Detalles Bibliográficos
Autores principales: Motorykin, Ievgen, Caulfield, Michael, McPhaul, Michael, Wu, Zengru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550859/
http://dx.doi.org/10.1210/js.2019-MON-487