Cargando…

MON-LB022 Gelesis Novel, Non-Systemic, Superabsorbent Hydrogel Improves Intestinal Barrier Function in Mice with DSS Induced Colitis

BACKGROUND: Intestinal barrier dysfunction exists when the epithelial tight-junctions are disrupted and permit translocation of bacterial lipopolysaccharides into the blood. The resulting endotoxemia cause systemic low-grade inflammation that contributes to the development of comorbidities associate...

Descripción completa

Detalles Bibliográficos
Autores principales: Silvestri, Alessandra, Lyng, Gregory, Parello, Caitlin, Graham, Sean, Chiquette, Elaine, Sannino, Alessandro, Rescigno, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550881/
http://dx.doi.org/10.1210/js.2019-MON-LB022