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MON-LB022 Gelesis Novel, Non-Systemic, Superabsorbent Hydrogel Improves Intestinal Barrier Function in Mice with DSS Induced Colitis
BACKGROUND: Intestinal barrier dysfunction exists when the epithelial tight-junctions are disrupted and permit translocation of bacterial lipopolysaccharides into the blood. The resulting endotoxemia cause systemic low-grade inflammation that contributes to the development of comorbidities associate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550881/ http://dx.doi.org/10.1210/js.2019-MON-LB022 |