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MON-LB039 Developmental Programming: Prenatal Testosterone Excess Induces Endoplasmic Reticulum (ER) Stress in the Metabolic Tissues of the Female Sheep

Prenatal exposure to excess testosterone (T) programs peripheral insulin resistance (IR) and dyslipidemia along with tissue-specific changes in ectopic lipid accumulation, oxidative stress and IR in liver and muscle, and inflammation, oxidative stress, and reduced adipogenesis, differentiation, and...

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Detalles Bibliográficos
Autores principales: Puttabyatappa, Muraly, Padmanabhan, Vasantha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550894/
http://dx.doi.org/10.1210/js.2019-MON-LB039